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Farmakoterapie tromboembolických stavů, 4. aktualizované vydání
Tromboembolické stavy patří svou prevalencí i následky k nejzávažnějším tématům současné medicíny i celého zdravotnického systému. Plicní embolizace u nás postihne ročně přes 6000 osob, přičemž mortalita dosahuje 7 až 11 %. V současnosti přibývá nemocných, kteří jsou buď krátkodobě – např. preventivně předoperačně – léčeni antitrombotiky, nebo na antitrombotické léčbě zůstávají dlouhodobě (při prevenci tromboembolických komplikací u fibrilace síní, po náhradách chlopní, v rámci léčby žilního tromboembolismu).
Čtvrté vydání úspěšné publikace dvou předních odborníků v oblasti angiologie a kardiologie přináší nejnovější poznatky v medikamentózní léčbě tromboembolických stavů, včetně podrobného seznámení s novými látkami na farmaceutickém trhu.
Kniha je určena jednak internistům a kardiologům, řadu terapeutických doporučení využijí rovněž praktičtí lékaři.
Sardinie - turistický průvodce
Poznejte Sardinii – jedinečný ostrov, kde se divoká příroda snoubí s autentickou kulturou a každá cesta se mění v nezapomenutelný zážitek.
Od členitých mysů a odlehlých písečných pláží až po zalesněné hory a rozlehlou divočinu – Sardinie je jedinečný středomořský ostrov, který překvapí i toho nejzkušenějšího cestovatele. Toužíte-li poznat kouzlo Karibiku či Tahiti, aniž byste opouštěli Evropu, měli byste zamířit právě sem. Chcete objevovat skryté poklady středověkého umění v nenápadných kostelích, ztratit se v živém bludišti úzkých uliček hlavního města Cagliari, ochutnávat výtečné víno, které se zde pěstuje několik tisíc let, nebo si zaplavat v tyrkysových vodách zátok na pobřeží? Tento plně aktualizovaný průvodce Rough Guide vám bude na vašich cestách nejlepším společníkem.
Z prestižní britské řady Rough Guides.
Anna, cesta ze Sudet
Anna Lesná dospívá ve světě, který se dramaticky mění. Z dívky poznamenané válečnými roky v Sudetech se stává mladá žena, jež se navzdory svému německému původu snaží vybojovat vlastní budoucnost. Jenže do života jejího i jejích blízkých se neúprosně vkrádá nová hrozba – nástup komunismu. Povinné brigády, tlak na vstup do strany, šeptanda o politických procesech a trestech smrti. Každý krok může být osudový. A přesto Anna odmítá ustoupit a vzdát se svých snů, touží studovat keramickou školu, složit maturitu a najít lásku.
Na pozadí proměňující se společnosti se odvíjí i další osudy – Lída Čechová prožívá hluboký cit ke studentovi techniky Miroslavovi, jenž se netají odporem k nastupujícímu režimu. Stačí však jediný čin a jeho život se ocitá v rukou moci, která neodpouští.
Vietor fúka do klobúka
Ak má niekto prievan v hlave, je to galiba. No ak by niekomu do nej niečo (múdre) len tak nafúkalo, bolo by to super. Nad básničkami v tejto knihe môžu malí čitatelia rozmýšľať, či sa vietor spod klobúka dostane aj inde. A pri hádankách, ktoré sú tiež jej súčasťou, si môžu cibriť svoj um a myslenie.
Tvorivé leto na Santorini
Tri ženy. Jedno leto na Santorini. A príbehy, ktoré im navždy zmenia život.
Keď bestsellerová autorka Jessica Rose prijme pozvanie viesť spisovateľský pobyt na oslnivom ostrove Santorini, dúfa, že medzi bielymi domčekmi, modrými kupolami a zlatými západmi slnka znovu nájde stratenú inšpiráciu. Pred minulosťou však nemožno utekať donekonečna. Zina sa na ostrov vracia po rokoch s jediným cieľom – premeniť svoj sen na úspešné podnikanie. Santorini je jej domovom, no zároveň miestom plným spomienok, ktoré nikdy celkom nevybledli. A Karmela? Tá túži napísať knihu, na ktorú bude jej matka hrdá. Netuší však, že práve toto leto jej prinesie oveľa viac než len príbeh na papieri.
A Summer Country Escape
The next book in the Country Escapes series!
You don't know what you've got till it's gone…
Bets Fowler has always been perfectly fine living her life firmly within the borders of her tiny village. But when her ex, Jack, returns and is suddenly everywhere she goes, she realises just how small the parameters of her existence have become, and starts to step outside her comfort zone.
Jack Ashcroft has always sought out a bigger life than he thought Wilsgrave could afford, but when a knockback sends him home, and back into Bets' orbit, he comes to see that the world he once inhabited has a lot more to offer than he ever realised, and that leaving might have been the biggest mistake he ever made.
Now, as Bets and Jack find themselves thrown together at every turn, the exes see what was and what could be in an entirely new light…
Pohledný ďábel
Gia: Netvor z nočních můr se vplížil do reality maskovaný jako můj šéf. Tatum Blackthorn je zosobněný Lucifer. Když odhalí moje slabé místo, udělá mi nabídku, kterou nemůžu odmítnout, a stanu se jeho ženou. Tate: Mám několik zálib a jednou z nich je zničit Giu Bennettovou. Pomalu. Trpělivě. Ta posedlost mojí asistentkou má důvod, ale žádné hranice. Jenže když se zapletu do války s mafií, není v ohrožení jen můj život. V šachové partii chrání král královnu. I za cenu toho, že obětuje celou svoji říši.
Daybreak - Sorrowsong University 2
Betrayal. Heartbreak. Deadly New Threats. Welcome Back to Sorrowsong University . . .
Alex Corbeau-Green's world is burning. Ophelia Winters is desperate to prove she didn't start the fire . . .
Ophelia came to the elite Sorrowsong University to destroy Alex and his family. But that was before she knew him. Before their love became each of their reasons for living.
Now, after an unthinkable betrayal and the disappearance of his father, Alex is forced back to New York. He is desperate to forget what they had - and salvage his empire. Ophelia is left behind in the Scottish Highlands, reeling, alone . . . and watched.
When a new, anonymous tormentor threatens to reveal evidence that Ophelia and Alex committed a murder on campus, it's clear they're going to need each other once again. But can they find a way to trust each other and repair the love they had?
And even if they can - will it be enough this time to keep them alive?
From Autumn Woods, Daybreak is the stunning conclusion to the Sunday Times bestseller Nightshade now - a dark academia romance brimming with snarky banter, shadowy figures, and sizzling tension.
The Plunge
A globe-spanning narrative adventure about how the euphoria of cold water can transform - and even extend - your life.
'Mesmerizing. Chris Ballard does a deep dive into one of the most controversial health, fitness, and athletic crazes of our time. I still loathe cold water, but I loved this book.' Adam Grant, #1 New York Times bestselling author of Think Again and Hidden Potential
Lifelong athlete and Sports Illustrated writer Chris Ballard worried his days of exercise were numbered. Then he received a fateful text message about a trend taking hold around the world: submerging in freezing cold water.
It wasn't only thrill seekers or wellness gurus extolling its power. Swimmers have long known that when paired with cold, their sport delivers extraordinary rewards; now, modern research has shown that just a few minutes in cold water can deliver remarkable benefits: heightened energy and focus, reduced inflammation, and relief from depression and anxiety.
In The Plunge, Ballard travels to laboratories and swims in waters around the world, from Portsmouth to the Pacific, tracing the roots of cold water swimming in ancient practices largely lost in the modern world.
He immerses himself in the growing tribe of cold-water junkies of all ages, shapes and nationalities, from pioneers like Lynne Cox to visionaries like Ram Barkai, whose audacious dream of getting ice swimming into the Olympics edges closer to reality.
And, from cold plunging to open water swimming to ice swimming, he tests his limits in this extreme sport, eventually becoming a US national champion, his body and mind transformed along the way.
Blending history, cutting-edge science, colourful characters, and propulsive narrative storytelling, it's a rollicking, eye-opening adventure that reveals how a single act - stepping into cold water - can unlock resilience, connection, meaning and joy.
Howl
Drawn from fifty years of experimental, ground-breaking verse, this selection, in Ginberg's words 'summarizes what I deem most honest, most penetrant of my writing'. It includes the major poems 'Howl' and 'Kaddish', but also important early work, songs, uncollected poems and notes from the author that go beyond his iconic Beat Generation image. Intensely personal and incandescently brilliant, Howl and Other Poems is a core Ginsberg text, and celebrates 'Holy the supernatural extra brilliant intelligent kindness of the soul!'
Selected Poems 1965-2005
'Tell me, what is it you plan to do
with your one wild and precious life?'
One of America's best loved poets, Mary Oliver is also among nature's most brilliant and devoted observers, whose words ask us to live with our eyes open wider. This luminous selection brings together her best-known works from across her career.
'Oliver's poems are … as genuine, moving, and implausible as the first caressing breeze of spring' New York Times Book Review
'Mary Oliver's poetry is fine and deep; it reads like a blessing' Stanley Kunitz
'Just a few seemingly simple phrases perfectly express what we need to know just then, in that moment' Oprah Winfrey
'It doesn't feel like you have to take a seminar in order to understand Mary Oliver's poetry. She's speaking directly to you as a human being' Ruth Franklin, The New Yorker
A Month in the Country
J. L. Carr's beautiful portrayal of the countryside and the healing it brings, in an irresistible Little Clothbound Classics edition designed by Coralie Bickford-Smith
'One of the best books I've ever read' Richard Osman
'Unlike anything else in modern English literature' D.J. Taylor, Spectator
A damaged survivor of the First World War, Tom Birkin finds refuge in the quiet village church of Oxgodby where he is to spend the summer uncovering a huge medieval wall-painting. Immersed in the peace and beauty of the countryside and the unchanging rhythms of village life he experiences a sense of renewal and belief in the future. Now an old man, Birkin looks back on the idyllic summer of 1920, remembering a vanished place of blissful calm, untouched by change, a precious moment he has carried with him through the disappointments of the years. Adapted into a film starring Colin Firth, Natasha Richardson and Kenneth Branagh, A Month in the Country traces the slow revival of the primeval rhythms of life so cruelly disorientated by the Great War.
Wreck
Rachel (Rocky) is seemingly living her best life as the irreverent, funny beating heart of her family. Her ageing father is his unique, adorable self; daughter Willa is prone to bouts of existential angst whilst berating the fact that her mother has zero filter; husband Nick is steady, logical, sometimes infuriating.
They are messy, they are flawed, they are completely, ridiculously normal.
And like most normal people, Rocky worries about what might happen next. So when a former classmate of her son Jamie dies in a seemingly random accident, Rocky becomes obsessed.
For if accidents can happen - and they do - is it truly safe to love anyone?
Fresh, honest, laugh out loud funny and genuinely relatable, WRECK follows Rocky and her family through one rollercoaster year as they negotiate the unpredictable and beautiful messiness of life.
If you love the brilliant humour and observation of Elizabeth Strout, Norah Ephron or Katherine Heiny, you will love Catherine Newman, who reminds us what it is to be beautifully messily human!
Odložené líbánky
Irisin svatební den Iris se stane internetovou senzací z těch nejhorších důvodů. Po hádce s nevěrným snoubencem odjíždí sama na líbánky na Kauai, odhodlaná začít znovu. Tam omylem sdílí bungalov se sexy cizincem Romanem Maguirem, hvězdou NFL, která skrývá vlastní tajemství. Co začne jako krátký románek v ráji, rychle přeroste v něco hlubšího. Jenže minulost, sláva i veřejná ostuda mohou jejich vztah zničit.
Animal Farm
One of the most celebrated works of modern literature, Animal Farm is George Orwell's satire on the Russian Revolution of 1917 and Stalin's subsequent rule. It tells the story of the animals of Manor Farm, as they rise up against the drunken farmer Mr Jones and the ensuing leadership battle between two pigs, Snowball and Napoleon. They set in motion their 'system of thought', Animalism, a clear play on Communism, with seven tenets including, 'All animals are equal but some animals are more equal than others.'
This elegant pocket hardback edition has real collector's appeal, featuring the classic, unabridged text, a facsimile of Orwell's signature on the title page, silver gilded page edges and beautifully designed endpapers. Part of the Arcturus Ornate Classics series this book makes wonderful gift for any lover of classic literature.
ABOUT THE SERIES: Arcturus Ornate Classics are beautifully bound editions of iconic literary works across history. These compact, foil-embossed hardbacks are printed using deluxe ivory paper and make the perfect gift.
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The Cafe at the End of the World
THE END IS BREWING ...
Love, lattes, and world-ending drama - life just got a lot less cosy for Lydie, teenage daughter of Death. The YA romcom/fantasy obsession you didn't know you needed.
Come for the cinnamon rolls, stay for the apocalypse.
Lydie, the daughter of Death, a retired Rider of the Apocalypse, is obsessed with 'cosy'; cosy books, cosy job in the family café, cosy low-drama life.
But then secretive, attractive, and above all annoying, Kai, bursts into the café in a flurry of autumn leaves, with secrets that threaten to change everything.
Big, un-cosy things are coming for Lydie whether she likes it or not, and working with Kai might be the only way to protect her town. Provided she doesn't fall for him first ...
TROPES FOR THE CAFÉ AT THE END OF THE WORLD
¤ Grumpy/sunshine
¤ Forced Proximity
¤ Enemies to ... well, that would be telling
¤ Brooding ML who just needs a hug
¤ 'I totally have to kiss you right now or else we'll blow our cover'
The Unselected Journals of Emma M. Lion, vol. 2
'I was sitting at my desk reading, with a cup of tea, my windows flung open, when I heard The Tenant enter his garret, just on the other side of the wall from myself.'
The year is 1883 and Emma M. Lion has returned to her London neighbourhood of St. Crispian's. But Emma's plans for a charmed and studious life are sabotaged by her eccentric Cousin Archibald, her formidable Aunt Eugenia, and the slightly odd denizens of St. Crispian's.
Emma M. Lion offers up her Unselected Journals, however self-incriminating they may be, which comprise a series of volumes. Armed with wit and a sideways amusement, Emma documents the curious realities of her life at Lapis Lazuli House.
Hello Baby
A cult feminist hit in South Korea, Hello Baby is a gripping and intimate portrait of motherhood, fertility and womanhood for fans of Butter and Breasts and Eggs.
Outside the chat, they had different jobs, personalities, financial backgrounds, but inside, they were all mothers-to-be anxiously awaiting their babies.
In a group chat called 'Hello Baby', six women share the anxieties and absurdities of undergoing IVF. They first met at Baby Angel Hospital, an elite fertility clinic in Seoul. Outside the chat, each woman is different - a journalist, a police officer, a vet, a lawyer and two housewives - but inside it, they've come to confide in one another. They know it is unlikely they will all get their happy ending, but while messaging, anything seems possible. So, when 46-year-old Jeong-hyo suddenly announces she has stopped treatment and goes silent, it rocks them all.
One year later, on Lunar New Year, Jeong-hyo sends a message announcing the birth of her daughter. As the stunned women count down to their visit to meet her and the new baby, they each reckon with their own journeys. Might this news hold fresh promise for each of them? To know that they will need to understand just how this unexpected miracle came to pass.
A cult feminist hit in South Korea, in this wry, courageous and disarmingly honest novel, Kim Eui-kyung, translated by Sora Kim-Russell, offers a unique and daring exploration of womanhood and motherhood today.
Najpredávanejší autori v tejto kategórii: Dominik Dán, Joanne K. Rowling, Freida McFadden, Elle Kennedy, Sarah J. Maasová.




























