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Farmakorezistentní epilepsie
Monografie je v české odborné literatuře je prvním obsahově komplexním textem věnovaným jednomu z nejžhavějších problémů současné epileptologie - praktické péči o pacienty s epilepsií, u nichž navzdory správně zvolené medikamentózní léčbě záchvaty př
etrvávají. Vlastní text je rozdělen do patnácti instruktivních a prakticky zaměřených kapitol, které jsou často doplněny bohatou obrazovou přílohu. Hlavní pozornost je věnována specifickým oblastem péče o pacienty s farmakorezistentní epilepsií mj.
příčinám intraktability, interdisciplinárnímu předoperačnímu vyšetření včetně semiinvazivních a invazivních postupů, problematice pseudofarmakorezistence, indikaci operační léčby, vlastním epileptochirurgickým zákrokům, psychiatrickým a sociálně-prá
vním aspektům farmakorezistentní epilepsie atd. Jednotlivé kapitoly odráží nejen bohaté zkušenosti autorů, ale zároveň poskytují i přehled současných vědomostí na dané téma. Vzhledem k pečlivému kolektivnímu zpracování teto složité problematiky a vla
stní struktuře jednotlivých kapitol lze předkládanou monografii současně využít jako přehledný edukační materiál pro specializované epileptologické vzdělávání.
Vypredané
58,59 €
61,67 €
Darwin's Ghosts
Christmas, 1859. Just one month after the publication of On the Origin of Species, Darwin received a letter that deeply unsettled him. He had expected criticism. Letters were arriving every day like swarms, some expressing praise, most outrage and accusations of heresy. But the letter from the Reverend Powell was different. It accused Darwin of failing to acknowledge his predecessors, of having taken credit for a theory that had already been discovered by others, Baden Powell himself and Darwin's own grandfather among them. For all the excuses that leapt to mind - publication had been rushed; he hadn't been well - Darwin knew he had made a grave error in omitting to mention his intellectual forebears. Yet when he tried to trace these natural philosophers, he found that history had already forgotten them...In Darwin's Ghosts, historian and novelist Rebecca Stott rediscovers Aristotle walking the shores of Lesbos with his pupils and Leonardo da Vinci searching for fossils in the mine shafts of the Tuscan hills; Diderot, in Paris, under the surveillance of the secret police, exploring the origins of species, and the brilliant naturalists of the Jardin de Plantes first recognising proof of evolutionary change in the natural history collections stolen during the Napoleonic wars. Darwin's Ghosts is a masterful retelling of the collective daring of a few like-minded men who had the imagination to speculate on nature's ways and the courage to publish at a time when to do so, for political as well as religious reasons, was to risk everything. More than a tale of mummified birds, inland lagoons, Bedouin nomads, secret police files, microscopes and curiosity cabinets, Darwin's Ghosts is the story of an idea that would change the modern world.
Vypredané
27,54 €
28,99 €
Langenscheidt Universal-Woerterbuch Spanisch
Das neu bearbeitete Universal-Wörterbuch Spanisch, herausgegeben vom Langenscheidt Fremdsprachenverlag beinhaltet über 33.000 Stichwörter und Wendungen mit klaren Bedeutungsdifferenzierungen und zahlreichen Anwendungsbeispielen. Neben dem allgemeinen Wortschatz gibt es viele Einträge aus den Bereichen Reise, Freizeit, Gastronomie, Sport und Fitness. Komplett neu ist der große Extrateil mit vielen Reisetipps von A - Z. Außerdem umfasst das Wörterbuch Informationen zu Zahlen, Speisekarten und einen Mini-Dolmetscher für wichtige Sprechsituationen. Mit den blauen Stichwörtern ist eine sehr schnelle Orientierung möglich. Zum schnellen Nachschlagen auf Reisen und für den fremdsprachlichen Anfangsunterricht.
Vypredané
7,10 €
7,47 €
Pyramiden
Der zum Assassinen ausgebildete Teppic, Sohn des Pharaos Teppicymon XXVII., soll die Nachfolge seines Vaters in dem kleinen Königreich Djelibeby antreten. Das Königreich, erfährt Teppic, ist so arm, daß es sich nicht einmal ordentliche Grabesflüche und Plagen leisten kann. Dennoch plant der neue Pharao, zu Ehren seines Vaters die größte Pyramide aller Zeiten zu bauen – ein aberwitziges Vorhaben, das die Vorfahren Teppics aus dem ewigen Schlaf erweckt und die Götter des Reichs herbeiruft. Glücklicherweise kann Teppic auf die Hilfe seines mathematisch begabten Kamels namens »Du Mistvieh« zählen …
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11,88 €
12,51 €
Tsubasa 5
THE END OF A FAIRY TALEFollowing the trail of the stolen children of Spirit Town, Sakura is captured at the forbidden castle, where she encounters the golden-haired ghost! Syaoran and his friends–the sociable magician Fai D. Flowright, the master swordsman Kurogane, and the odd creature Mokona–must now penetrate the ancient stronghold in order to rescue Sakura and the missing children. Will they finally uncover the truth behind the legend of Princess Emerald? And will they recover another fragment of Sakura’s lost memory?
Vypredané
14,57 €
15,34 €
Lacná kniha Pyramiden (-90%)
Der zum Assassinen ausgebildete Teppic, Sohn des Pharaos Teppicymon XXVII., soll die Nachfolge seines Vaters in dem kleinen Königreich Djelibeby antreten. Das Königreich, erfährt Teppic, ist so arm, daß es sich nicht einmal ordentliche Grabesflüche und Plagen leisten kann. Dennoch plant der neue Pharao, zu Ehren seines Vaters die größte Pyramide aller Zeiten zu bauen – ein aberwitziges Vorhaben, das die Vorfahren Teppics aus dem ewigen Schlaf erweckt und die Götter des Reichs herbeiruft. Glücklicherweise kann Teppic auf die Hilfe seines mathematisch begabten Kamels namens »Du Mistvieh« zählen …
Vypredané
1,25 €
12,51 €
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GraviTrax Power Elektronické doplnky Ravensburger
Veľká sada všetkých elektronických doplnkov z radu GraviTrax Power, vrátane ovládača elektronických prvkov, pre nekonečnú GraviTrax jazdu. Elektronické doplnky medzi sebou komunikujú – vysielajú a prijímajú signály. Akonáhle guľôčka prejde Spúšťačom, spustí sa signál. Hráč určí, či má na signál reagovať Výhybka, Štartér alebo akčný kameň Páka. K zvoleniu dráhy guľôčky je možné použiť ovládač elektronických doplnkov, ktorý je súčasťou balenia. Elektronické Schodisko automaticky vyváža guľôčky na poschodie bez nutnosti ručného resetovania. Tým sa generuje nová energia a prakticky nekonečná jazda môže začať. Toto rozšírenie je možné plne použiť iba s jednou zo štartových sád GraviTrax.
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219,99 €
Girlboss
"A #GIRLBOSS is in charge of her own life. She gets what she wants because she works for it." The first thing Sophia Amoruso sold online wasn't fashion--it was a stolen book. She spent her teens hitchhiking, committing petty theft, and dumpster diving. By twenty-two, she had resigned herself to employment, but was still broke, directionless, and working a mediocre day job she'd taken for the health insurance. It was there that Sophia decided to start selling vintage clothes on eBay. Eight years later, she is the founder, CEO, and creative director of Nasty Gal, a $100 million plus online fashion retailer with more than 350 employees. Sophia's never been a typical CEO, or a typical anything, and she's written #GIRLBOSS for outsiders (and insiders) seeking a unique path to success, even when that path is winding as all hell and lined with naysayers. #GIRLBOSS includes Sophia's story, yet is infinitely bigger than Sophia. It's deeply personal yet universal. Filled with brazen wake-up calls ("You are not a special snowflake"), cunning and frank observations ("Failure is your invention"), and behind-the-scenes stories from Nasty Gal's meteoric rise, #GIRLBOSS covers a lot of ground. It proves that being successful isn't about how popular you were in high school or where you went to college (if you went to college). Rather, success is about trusting your instincts and following your gut, knowing which rules to follow and which to break. A #GIRLBOSS takes her life seriously without taking herself too seriously. She takes chances and takes responsibility on her own terms. . She knows when to throw punches and when to roll with them. When to button up and when to let her freak flag fly. As Sophia writes, "I have three pieces of advice I want you to remember: Don't ever grow up. Don't become a bore. Don't let The Man get to you. OK? Cool. Then let's do this."
Vypredané
18,00 €
18,95 €
MOONSTONE
Introduction and Notes by David Blair, Rutherford College, University of Kent The Moonstone, a priceless Indian diamond which had been brought to England as spoils of war, is given to Rachel Verrinder on her eighteenth birthday. That very night, the stone is stolen. Suspicion then falls on a hunchbacked housemaid, on Rachel's cousin Franklin Blake, on a troupe of mysterious Indian jugglers, and on Rachel herself. The phlegmatic Sergeant Cuff is called in, and with the help of Betteredge, the Robinson Crusoe-reading loquacious steward, the mystery of the missing stone is ingeniously solved.
Vypredané
4,38 €
4,61 €
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Oxford Bookworms Library 3 Goldfish
The Leander pearls were stolen nineteen years ago. The thief was caught, but the pearls were never found, and there is still a 25,000 reward for anyone who finds them. Then somebody comes to private detective Carmady with a story about a guy who knows where the pearls are hidden. Carmady agrees to talk to the guy who says he knows. But he finds him dead in his bed, with burned feet, and it seems there are quite a lot of people in Los Angeles who have heard the story, and who are out looking for the Leander pearls
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3,94 €
4,15 €
Hotel Havanna - 16 szelíd történet
A Hotel Havanna elsősorban érettségével, az írói eszközök eredményes használatával lepi meg az olvasót. Hidas Judit jól ért annak szemléltetéséhez, hogy a szeretetfüggő emberek gyengeségük fitogtatásával hogyan kerekednek a másik ember fölé. A szerző finom iróniája és a jelenetek sok meghökkentő fordulata pedig mindezt mulatságossá is teszi. Hidas Judit vérbeli elbeszélő, és más, nemrég jelentkezett fiatal írókkal, Szvoren Edinával, Csobánka Zsuzsával, Potozki Lászlóval, Szabó Róbert Csabával együtt a magyar elbeszélés egyik megújítójának ígérkezik." (Marton László) A kötet alcíme "szelíd történeteket" ígér, de ez ne tévesszen meg senkit. A Hotel Havannában összegyűjtött írások kegyetlen szövegek. A zavarba ejtő az, hogy mindebben nincs semmi rendkívüli. A történetek a mai Magyarországon játszódnak, és minduntalan ráismerünk az alakokra, a helyzetekre. A kép aggasztó, de hiteles."
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7,27 €
7,65 €
Langenscheidt Fussball - Deutsch / Deutsch - Fussball
Was Sie schon immer über Fußball wissen wollten, ... Von Gerhard Delling. Mit einem Augenzwinkern und viel Sprachwitz wird Wissenswertes und Amüsantes rund um den Fußball präsentiert. - Wollten Sie schon immer wissen, woher die Arschkarte" stammt, was die Zahlen "54 74 90" bedeuten und wer "Leo" ist? - Die Antworten darauf und mehr findet man in den Kapiteln "Hätten Sie's gewusst?", "Er sagt er meint" und "Frau und Fußball". - Dazu gibt es "Fußballwitze", "Schlaue Sprüche" wie auch "Dumme Sprüche" und dazwischen eine bunte Mischung aus humorvollen Erklärungen bekannter und weniger bekannter Fußballbegriffe wie "pressen" und "Pferdekuss". - Durchgehend farbig mit vielen Zeichnungen von Ulf Harten und einem Bild von Rudi Kargus (ehemaliger Nationaltorwart). - Das ultimative Werk für alle Fußballfans und solche, die es werden wollen."
Vypredané
2,85 €
3,00 €
Inca Gold
Dirk Pitt® is back, in a adventure that is perhaps the most inventive and most exciting of his career - a classic treasure hunt involving an ancient hoard of gold, the secrets of a lost civilization, and an international ring of smugglers, all brought together in a plot that only Clive Cussler could devise. Inca Gold begins in 1532, when a fleet of ships sails in secret to an island in the middle of an inland sea. There they hide a magnificent treasure more vast than that of any pharaoh. Then they disappear, leaving only a great stone demon to guard their hoard. In 1578 the legendary Sir Francis Drake captures a Spanish galleon filled with Inca gold and silver and the key to the lost treasure, which included a gigantic chain of gold that belonged to the last Inca king, a masterpiece of ancient technology so huge that it requires two hundred men to lift it. As the galleon is sailed by Drake's crew back to England, an underwater earthquake causes a massive tidal wave that sweeps it into the jungle. Only one man survives to tell the tale... In 1998 a group of archaeologists is nearly drowned while diving into the depths of a sacrificial pool high in the Andes of Peru. They are saved by the timely arrival of Dirk Pitt, who is in the area on a marine expedition. Pitt soon finds out that his life has been placed in jeopardy as well by smugglers intent on uncovering the lost ancient Incan treasure. Soon, he, his faithful companions, and Dr. Shannon Kelsey, a beautiful young archaeologist, are plunged into a vicious, no-hold-barred struggle to survive. From then on it becomes a battle of wits in a race against time and danger to find the golden chain, as Pitt finds himself caught up in a struggle with a sinister international family syndicate that deal in stolen works of art, the smuggling of ancient artifacts, and art forgery worth many millions of dollars. The clash between the art thieves, the FBI and the Customs Service, a tribe of local Indians, and Pitt, along with his friends from NUMA, two of whom are captured and threatened with execution, rushes toward a wild climax in a subterranean world of darkness and death - for the real key to the mystery, as it turns out, is a previously unknown, unexplored underground river that runs through the ancient treasure chamber. Inca Gold is Clive Cussler - and Dirk Pitt - at their very best."
Vypredané
6,27 €
6,60 €
Conspiracies of Rome
The Roman Empire is dead—long live the church of Rome! A new series of historical thrillers introduces the most compelling anti-hero since Flashman 609 AD. Rome is torn apart by war, plague, and internal power struggles between the emperor, the aristocracy, and the church. Into this morass stumbles the young and handsome Briton Aelric. His father was murdered, his inheritance was stolen, and he was forcibly separated from the woman he loves—now he is determined to win back all that he has lost. Through his naivety and ambition, he unwittingly becomes involved in a heretical plot that will lead to fraud, high treason, and murder. The first in a searingly sharp trilogy, this adventure takes readers back to one of the darkest and least known periods of history.
Vypredané
9,45 €
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Az Éjféli Kristály
Az Álomfény-trilógia egy több nemzedéket sújtó családi átok története. Harmadik könyve a távoli jövőbe, egy másik világba röpíti a kedves Olvasót.
A Harmónia bolygón a mélység esőerdőket rejteget, a rég eltűnt, idegen civilizáció titokzatos emlékeit
hátborzongató, zölden foszforeszkáló városromok és labirintusok őrzik, furcsa állatok szegődnek az emberek társául, és a bolygó szinte minden lakója rendelkezik valamiféle pszichikus képességgel.
Ebben a különös világban Adam Wintersre, a Szellemvad
ász Céh új vezetőjére sújt le az ősi átok. Ezúttal neki kell megtalálnia az elveszett Lámpát és az álomfényfejtő nőt, aki azonban nem más, mint a Winters család egykori ellenségének, Sylvester Jonesnak a leszármazottja, Marlowe Jones.
Adam és Marlowe
útja izzó katakombák és föld alatti dzsungelek csapdáin keresztül vezet, de a köztük fellobbanó vágyakozás elsöprő ereje minden kelepcénél veszélyesebb. Vajon a szerelem, a forró szenvedély le tudja-e győzni Nicholas Winters pusztító bosszúját, megt
örik-e végre a rettenetes átok? Itt, a Harmónián minden titokra fény derül...
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3,00 €
The Pleasures of Spring
This is an invitation to the hot and steamy world of bestselling Irish erotica author Evie Hunter..."More colour and better written than EL James and a more exciting read than any of Sylvia Day's books". (Irish Independent). "A BDSM masterpiece". (Sunday World). "A must-read if you enjoyed Fifty Shades of Grey". (Irish Daily Star). He picked up her hand where it grasped the water glass, felt her pulse and looked into her eyes. 'You don't want a man with manners. You want someone who will let you walk on the wild side, who knows what you're really like...' Roz Spring is an actress and a chameleon, the kind of woman who always lands on her feet. But even Roz can't talk her way out of witnessing a murder, and she must go into hiding before the murderer comes for her. Andy McTavish has turned his back on a life of privilege to prove himself in the world of international security. Tall, dark and dangerous, Andy is the ultimate seducer who has never met a woman who can tame him. Roz needs his protection and, to get his family off his back, Andy needs a fake fiancee. The solution is obvious: pretend to be a couple. Getting up close and personal won't be hard, as the chemistry between them is electrifying. As two practiced charmers drive each other beyond the limits of sensual endurance, they find their usual defences are no good. When the barriers come crashing down, a raw passion emerges that neither wants to admit. They know that when the murderer shows his hand, they will face a fight for life and freedom. And if they survive, what will happen when the need to pretend is over? The Pleasures of Spring is the latest sizzling standalone novel from Evie Hunter whose trademark combination is an addictive erotic story and a page-turning plot. If you're an Evie fan, you won't be disappointed. And if you're new to Evie, well, you're in for quite the delicious treat...Praise for Evie Hunter: "As near perfection as a Suspense/Romance/Erotic/BDSM novel could EVER get!" (Ripe for Reader). "Every delicious moment comes with amazing tension and believability ...masterfully written, artfully told, and yummy to read". (My Book Boyfriend). "All I can say is, holy yowza, Batman! Yes, this book falls firmly into the 'What to read after Fifty Shades of Grey' category, but in my opinion ...this book blows Fifty Shades out of the water. I unabashedly adored this book". (This Bookish Endeavor). "Danger, heat, obsession and unexplored desires come together to form a combustive and sizzling tale, not soon forgotten". (Romancing The Book). "One of those rare books that has stolen my heart, my mind and my soul ...a flawless, exciting and down-right steamy read that will stay with you long after your finish". (Totally Bookalicious).
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9,98 €
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Lost Light
At the end of CITY OF BONES Harry Bosch quit the LAPD, but he's back in a new role, one that will give him more freedom to pursue the cases that compel him. When he left the LAPD Bosch took a file with him: the case of a film production assistant murdered four years earlier during a $2 million robbery on a movie set. The LAPD, now operating under post 9/11 rules, thinks the stolen money was used to finance a terrorist training camp. Thoughts of the original murder victim were lost in the federal zeal, and when Bosch decides to re-investigate, he quickly falls fouls of both his old colleagues and the FBI. But it's not just the case which is keeping Bosch awake at night. When the investigation enables him to meet up with an old friend, shadows from his past come back to haunt him...
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6,65 €
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Dětská neurologie
V dětské neurologii došlo v posledních letech k významnému pokroku. Tím, že se u dosud pouze klinicky definovaných jednotek (např. Rettův syndrom, Angelmanův syndrom, spinocerebelární ataxie) v současnosti otevřela možnost postavit diagnózu na podkla
dě molekulárně genetického vyšetření, mění se i celkový pohled na okruhy neurometabolických, neurodegenerativních a nervosvalových poruch. Nové poznatky v epileptologii přináší magnetická rezonance a video-EEG, moderní antikonvulzívní terapie zahrnuj
e antiepileptika 3. generace. Podstatné jsou pokroky v neuroonkologii, neuroimunologii a relativně nový je koncept neurovývojových onemocnění zahrnující dříve opomíjený autismus.
Tato publikace, koncipovaná jako vybrané kapitoly z dětské neurologie,
nemá být a není kompletní učebnicí. Jednotlivá témata byla volena podle aktuálního programu výuky dětské neurologie s cílem poskytnout čtenářům základní orientaci v problematice a medikům podklad pro aktivní účast na přednáškách. Kapitoly upozorňují
na odlišnosti neurologie dětí a dospělých a zahrnují osvědčené postupy vývojového neurologického vyšetřování novorozenců a kojenců.
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12,96 €
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WoodWick sviečka veľká Oudwood
Zvodné jantárové a aromatické drevo tavené s krémovou vanilkou a podtónmi kadidla.
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33,90 €