The Bodley Head

From butcher's daughter in communist Hungary to winner of the Nobel Prize in Medicine, this is the story of one woman's extraordinary determination and her breakthrough discovery that saved millions of lives. Katalin Karikó began life as a butcher's daughter in communist Hungary. Raised in a one-room home of clay and straw with no running water, she saw potential everywhere: in the promise of a seed, in the alchemy of soap, in the scarlet of a carcass. Breaking Through is the extraordinary story of her courageous determination - first to become a scientist, and then to unlock an elusive molecule she believed could revolutionise medicine. Others disagreed, and for decades she endured demotions, discrimination and even threats of deportation. Yet Karikó persevered, ultimately making a world-shifting discovery: the mRNA vaccine technology that saved millions of lives and will transform healthcare forever.

The smash-hit Sunday Times bestseller now illustrated with over 100 spectacular full-colour images, showcasing this wondrous and wildly various lifeform as never before *WINNER OF THE ROYAL SOCIETY BOOK PRIZE 2021* *WINNER OF THE WAINWRIGHT PRIZE FOR CONSERVATION WRITING 2021* The more we learn about fungi, the less makes sense without them. They can change our minds, heal our bodies and even help us avoid environmental disaster; they are metabolic masters, earth-makers and key players in most of nature's processes. In Entangled Life, Merlin Sheldrake takes us on a mind-altering journey into their spectacular world, and reveals how these extraordinary organisms transform our understanding of our planet and life itself.

The second volume of Clinton Heylin's magisterial biography takes us from Dylan's 1966 motorcycle accident to the present day. We meet a man who is determined to confound expectations; yet whatever he does only seems to confirm his iconic status to fans and critics alike. There are peaks and troughs. Long periods of writer's block are followed by sudden bursts of creativity that produce some of the best work of his career, including perhaps his most celebrated album, 1975's Blood On The Tracks. There is the unpredictable recording process, with Dylan often including on his albums the worst takes and leaving off the best songs altogether. On the Neverending Tour he reinvents his songbook on a nightly basis, at times without recognition. Then there are the albums and songs that reveal the genius of an artist whose lyrics draw on centuries of American culture but who refuses to be shackled to his own past. Today his voice is almost unrecognisable from his 1960s peak, and the man whose songs had been devoted to dissecting his romantic relationships has become focused on mortality, solitude and getting old. Yet his albums continue to top the charts, 2020's Rough And Rowdy Ways being his fourth No. 1 album of the twenty-first century. There is no other living artist whose creative output has remained constantly intriguing, often baffling, sometimes infuriating but always fascinating for over sixty years. Clinton Heylin's definitive, scrupulously researched and revelatory life, based on unprecedented access to the official Tulsa archive and other new sources, paints the fullest and brightest portrait yet of an iconic figure that has defined contemporary culture.

A neuropsychologist takes ten different drugs in this panoramic view of psychedelics today Once demonised and still largely illegal, psychedelic drugs are now officially a 'breakthrough therapy', used to treat depression, trauma and addiction and to enhance well-being. But as neuropsychologist Andy Mitchell shows in this deeply serious yet wildly entertaining investigation, this approach misses what is so strange and valuable about them: the psychedelic experience itself. In Ten Trips he takes ten different drugs in ten different settings, journeying from a neuroimaging lab in London to the Colombian Amazon via Silicon Valley and his friend's basement kitchen. His encounters with scientists and gangsters, venture capitalists and con-men, psychonauts and shamans provide a panoramic view of psychedelics today: their capacity for healing but also trauma, for transcendence and corruption, profundity and hilarity. By removing psychedelics from their indigenous and underground cultures, we risk losing the very things we need to harness them. To make them safe or normal might ultimately destroy what makes them potent. That potential is indeed great, not as an antidote to mental illness - none exists - but as a way of changing our whole perspective on mental health and flourishing. Ten Trips is a dazzling, perception-shifting odyssey that shows how psychedelics can re-enchant us with the world.

AI. SYNTHETIC BIOLOGY. QUANTUM COMPUTING. Everything is about to change. This is the only book you need to understand this new world. From the ultimate AI insider, Mustafa Suleyman, co-founder of DeepMind, part of Google. Soon you will live surrounded by AIs. They will organise your life, operate your business, and run core government services. You will live in a world of DNA printers and quantum computers, engineered pathogens and autonomous weapons, robot assistants and abundant energy. None of us are prepared. As co-founder of the pioneering AI company DeepMind, part of Google, Mustafa Suleyman has been at the centre of this revolution. The coming decade, he argues, will be defined by this wave of powerful, fast-proliferating new technologies. In The Coming Wave, Suleyman shows how these forces will create immense prosperity but also threaten the nation-state, the foundation of global order. As our fragile governments sleepwalk into disaster, we face an existential dilemma: unprecedented harms on one side and the threat of overbearing surveillance on the other. Can we forge a narrow path between catastrophe and dystopia? This ground-breaking book from the ultimate AI insider establishes 'the containment problem' - the task of maintaining control over powerful technologies - as the essential challenge of our age.

The first book about the science of how, why and what happens when we talk, from the author of In Praise of Walking Talking Heads is a stunning survey of the science of human connection and communication - from neurons to nations We are social animals and talking is a defining part of what makes us human. Chatting with friends or debating the future, we move through life in a state of near-constant dialogue, bridging the gap between our inner and outer worlds. But what purposes does conversation serve? In this revelatory tour of the science of talking, neuroscientist Shane O'Mara explores how and why we communicate, what is happening in our brains when we do it, and what it means for us as individuals, groups and societies. Our brains create our realities, but we shape them by talking. How do our thoughts, memories, and conversations change the very fabric of our brains? What does it mean that we spend the majority of our thinking lives in a five-minute bubble around the present moment? Why does our sense of self solidify with age, even as we become more forgetful? How does our default mode of trusting what others say both influence life as we know it and empower us to effect change? What does it mean to say we imagine futures together? And how do our very nations begin as conversations? Moving from the personal to the social and ultimately towards a radical new perspective on the defining phenomenon of our times, populist nationalism, this is the story of how conversation builds the worlds around us - and how, together, we can talk our way into a better tomorrow.

A revelatory portrait of life in a great museum and the moving story of one guard's quest to find solace and meaning in art Millions of people climb the grand marble staircase into New York's Metropolitan Museum of Art every year. Patrick Bringley never thought he'd be one of them. But when his brother was diagnosed with fatal cancer he quit his journalism job, and sought peace in the most beautiful place he knew. To his surprise, this temporary refuge becomes his home away from home for a decade. Bringley enters the museum as a ghost, silent and almost invisible, but soon finds his voice and place among the lively subculture of museum guards. As his bonds with colleagues and the art grow, he learns how fortunate he is to be walled off in this little world and how much it resembles the best aspects of the larger world to which he gradually, gratefully returns.

The heart of racism is denial. It is refusing to self-reflect. In his global, game-changing bestseller How To Be An Antiracist Ibram X. Kendi, director of the Centre for Antiracist Research at Boston University, showed that when it comes to racism, neutrality is not an option: until we become part of the solution, we can only be part of the problem. Crucially, it requires 'persistent self-awareness, constant self-criticism and regular self-examination'. In this workbook he uses his extraordinary gifts as a teacher to provide the reader with a series of activities, exercises and reflections to help them do this vital work, to cultivate an instinctive awareness of racism in all its forms and to take the action necessary to promote racial equity in the world around them. He asks us to reflect on our thinking around race through prompts including 'Describe the most racist moment of your life,', 'Have you ever been hesitant to use the R-word? Why?' and 'What does resistance mean to you?' helping us understand that the heartbeat of anti-racism is confession. It is self-reflection. Being antiracist is not something you are. It's something we do.

In a centuries-old tradition, farmers in northwestern Iceland scour remote coastal plains for the down of nesting eider ducks. High inside a vast cave in Borneo, men perched atop rickety ladders collect swiftlets' nests, a delicacy believed to be a cure for almost anything. Eiderdown and edible birds' nests: both are luxury products, ultimately destined for the super-rich. To the rest of the world these materials are mere commodities but to the harvesters they are all imbued with myth, tradition, folklore and ritual, and form part of a shared identity and history. These objects are two of the seven natural wonders whose stories Harvest tells: eiderdown, vicuna wool, sea silk, vegetable ivory, civet coffee, guano and edible birds' nests. Harvest follows their journey from the wildest parts of the planet, traversing Iceland, Indonesia, and Peru, to its urban centres, drawing on the voices of the gatherers, shearers and entrepreneurs who harvest, process and trade them. Blending interviews, history and travel writing, Harvest sets these human stories against our changing economic and ecological landscape. What do they tell us about capitalism, global market forces and overharvesting? How does a local micro-economy survive in a hyper-connected world? Harvest makes us see the world with wonder, curiosity and new concern. It is an original and magical new map of our world and its riches.

The past is another country, the old saying goes. The same might be said of the future. But which country? For Europeans and Americans today, the answer is Russia. Today's Russia is an oligarchy propped up by illusions and repression. But it also represents the fulfilment of tendencies already present in the West. And if Moscow's drive to dissolve Western states and values succeeds, this could become our reality too. In this visionary work of contemporary history, Timothy Snyder shows how Russia works within the West to destroy the West; by supporting the far right in Europe, invading Ukraine in 2014, and waging a cyberwar during the 2016 presidential campaign and the EU referendum. Nowhere is this more obvious than in the creation of Donald Trump, an American failure deployed as a Russian weapon. But this threat presents an opportunity to better understand the pillars of our freedoms, confront our own complacency and seek renewal. History never ends, and this new challenge forces us to face the choices that will determine the future: equality or oligarchy, individualism or totalitarianism, truth or lies. The Road to Unfreedom helps us to see our world as if for the first time. It is necessary reading for any citizen of a democracy.

Jaron Lanier, ‘the father of Virtual Reality … a high-tech genius’ (Sunday Times), tells the extraordinary story of how in just over three decades Virtual Reality went from being a dream to a reality – and how its power to turn dreams into realities will transform us and our world. Virtual Reality has long been one of the dominant clichés of science fiction. Now Virtual Reality is a reality: those big headsets that make people look ridiculous, even while radiating startled delight; the place where war veterans overcome PTSD, surgeries are trialled, aircraft and cities are designed. But VR is far more interesting than any single technology, however spectacular. It is, in fact, the most effective device ever invented for researching what a human being actually is – and how we think and feel. More than thirty years ago, legendary computer scientist, visionary and artist Jaron Lanier pioneered its invention. Here, in what is likely to be one of the most unusual books you ever read, he blends scientific investigation, philosophical thought experiment and his memoir of a life lived at the centre of digital innovation to explain what VR really is: the science of comprehensive illusion; the extension of the intimate magic of earliest childhood into adulthood; a hint of what life would be like without any limits. As Lanier shows, we are standing on the threshold of an entirely new realm of human creativity, expression, communication and experience. While we can use VR to test our relationship with reality, it will test us in return, for how we choose to use it will reveal who we truly are. Welcome to a mind-expanding, life-enhancing, world-changing adventure.

London in the eighteenth century was very much a new city, risen from the ashes of the Great Fire. With thousands of homes and many landmark buildings destroyed, it had been brought to the brink. But the following century was a period of vigorous expansion, of scientific and artistic genius, of blossoming reason, civility, elegance and manners. It was also an age of extremes: of starving poverty and exquisite fashion, of joy and despair, of sentiment and cruelty. Society was fractured by geography, politics, religion and history. And everything was complicated by class. As Daniel Defoe put it, London really was a 'great and monstrous Thing'. Jerry White's tremendous portrait of this turbulent century explores how and to what extent Londoners negotiated and repaired these open wounds. We see them going about their business as bankers or beggars, revelling in an enlarging world of public pleasures, indulging in crimes both great and small - amidst the tightening sinews of power and regulation, and the hesitant beginnings of London democracy. In the long-awaited finale to his acclaimed history of London over 300 years, Jerry White introduces us to shopkeepers and prostitutes, men and women of fashion and genius, street-robbers and thief-takers, as they play out the astonishing drama of life in eighteenth-century London.